Nabilone (Synthethic Cannabinoid) For Treating PTSD Nightmares

A recently published study of 10 Canadian military male subjects resulted in a 50% 'very much improved' treatment regime in reducing the frequency and intensity of nightmares in subjects with PTSD. "The endocannabinoid system may be involved in the pathophysiology of PTSD. One recent imaging study implicates a lower endocannabinoid tone in PTSD, specifically in the amygdala—hippocampal—cortico-striatal circuitry." (adsbygoogle = window.adsbygoogle || []).push({}); "At the end of the NAB treatment period 7 out of 10 subjects (70%) scored as very much improved or much improved, compared to 2 out of 9 (22%) at the end of the PBO treatment period." Whilst the study is far from empirical due to the low participation factor, the results are interesting nonetheless. A Nabilone capsule (NAB) of 0.5mg, titrated to a maximum effective dosage of 3.0mg was used over a 7 week period. As a double blind study, the subjects were then exposed to other treatments for the same duration. "The effect
https://www.ptsdnews.com/item/6-nabilone-synthethic-cannabinoid-for-treating-ptsd-nightmares